Cocktail Bars in Santiago
The best cocktail bars in Santiago range from pisco-led rooms to a bar with live music every night. In Las Condes, a pisco bar on Isabel La Católica pours contemporary Chilean cocktails alongside more than eighty labels of pisco. Providencia has a bar built around the Negroni and a live-music room, the sibling of a Buenos Aires original. A Thai restaurant in Barrio Italia runs a cocktail bar of its own, and Vitacura pairs drinks with Mexican street food at CV Galería. A tip: the speakeasy in La Reina stays out of sight behind a specialty coffee shop, so walk into the café first. These are the six we would start with.
- Siete Negronis50 BESTCocktail Bar
Siete Negronis
Siete Negronis is the Providencia cocktail bar named for the drink it is built around, now at Constitución 241 at the Bellavista end of the neighborhood. Its Instagram carries the menu, the music and the bookings link; the website is under construction.
Constitución 241, Providencia, SantiagoFull profile - Siam ThaiCocktail Bar
Siam Thai
Siam Thai is a Thai restaurant and cocktail bar at Avenida Italia 1139 in Santiago's Barrio Italia, in the Providencia district. Guests can settle at the bar, in the dining room, on the patio or out on the terrace, and the kitchen gets as much attention as the drinks. Sharing is encouraged, with boards and plates of Thai dishes to pass around. The latest signature list takes precious stones as its theme: El Rubí is a sparkling drink built on rum and passion fruit liqueur, sweetened with Chilean palm syrup steeped in toasted flour, while the Ópalo mixes blended Scotch, tamarind and a horchata of chestnut and cassia. Alcohol-free cocktails and house juices are also offered. Tables can be reserved online, and the bar opens in the evening Monday to Thursday and from lunchtime Friday to Sunday.
Francisco Bilbao 581, SantiagoFull profile 
SpeakeasyEnigma
Enigma is a hidden speakeasy in La Reina, Santiago, opened in December 2022 around a theme of mystery, science and ritual. Guests first walk into Café Enigma, a neighborhood specialty coffee shop, and the bar stays out of sight until someone cracks a Fibonacci puzzle and the wall gives way. Inside are three rooms: a Gothic Room, an English Room where the bar sits among brass, marble and dark wood, and a Steampunk Terrace. A 50 Best guide to Santiago noted its intrigue and its Chilean touch. Relaunched in 2026 as Enigma 2.0, it now pours ten signature cocktails drawn from world enigmas and legends, alongside a list of more than 70 wines.
Av. Larraín 5941, La Reina, SantiagoFull profile- BackroomCocktail Bar
Backroom
Backroom is the Santiago sibling of Backroom Bar in Buenos Aires, the venue La Tercera sums up as a jazz club, bookshop and signature cocktail bar rolled into one. It sits on Pérez Valenzuela in Providencia, and La Tercera picked it among ten new Santiago bars to put on any night out, calling it a new and remarkable place to hear live jazz. From the street it passes for just another house on the block, but inside the look is bohemian, recalling the jazz clubs of old, with interiors by the design duo Grisanti & Cussen and tall shelves stacked with books and records. At its heart is a stage where live music plays every night.
Pérez Valenzuela 1470, Providencia, SantiagoFull profile - Bar La ProvidenciaCocktail Bar
Bar La Providencia
Bar La Providencia describes itself in three lines: contemporary Chilean cocktails, greedy cooking, and more than eighty labels of pisco. It sits on Isabel La Católica in Las Condes, takes reservations by email, runs a guest-bartender program and hires out for events. Open Monday to Thursday from six until half past midnight and until one on Friday and Saturday.
Isabel La Católica 4208, Las Condes, SantiagoMon-Thu 18:00-00:30, Fri-Sat 18:00-01:00Full profile
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More of Santiago
These are the cocktail bars specifically. The full Santiago guide ranks the best bars of every style, and the directory lists all 9 with a map and filters.
