Six cocktail bars in Macau, including one on Asia's 50 Best.

The St. Regis Bar sits on the second floor of The St. Regis Macao within The Londoner Macao, carrying the brand's New York heritage and its jazz legacy into a contemporary room. Its signature is Maria do Leste, a Macao reading of the St. Regis Bloody Mary built around the city's east-meets-west identity, and the bar also runs an afternoon tea service.
Mesa Bar is the bar of Mesa by José Avillez, the contemporary Portuguese restaurant on Level 3 of The Karl Lagerfeld at Grand Lisboa Palace in Cotai. The room weaves Chinese iconography into Karl Lagerfeld's black, white and gold style, and the bar itself is a central island modeled on a birdcage. Resort Master Mixologist Frederick Ma builds drinks that tell stories of Portuguese and Chinese heritage and trace the old sea routes between Lisbon and Macau, among them the Casa de Abelha and Holy Wood. Herbs are grown in house, fruit remnants from the kitchen become kombucha and mead, and the spirits come from ecoSPIRITS. It was No. 82 on the Asia's 50 Best Bars 51-100 list in 2022.

Goa Nights opened in 2018 in Old Taipa Village, one of the first independent craft cocktail bars in a city of hotel bars. Co-founder Gagan Sethi runs it with his wife Gwen Trott and his sister Shilpa Sethi, and the drinks draw on Goa's past as a Portuguese colony. In August 2024 it moved to a larger space on Broadway Food Street at Broadway Macau, with outdoor seating. Cocktails such as the St Paul's Ruins are made from scratch, with spirits infused in house with cardamom and cumin. Indian and Goan plates come alongside, and guests can step behind the bar to shake their own drink. It was No. 100 on the Asia's 50 Best Bars 51-100 list in 2021.

At the heart of Wynn Palace, Wing Lei Bar is a crossroads where East meets West. Wynn Palace hosted the Asia's 50 Best Bars 2025 awards ceremony, and the bar is helmed by Head Mixologist Mark Lloyd.
Two Moons sits on Rua de Pedro Nolasco da Silva in the historic center of Macau, directly across from the Consulate General of Portugal, and was opened in 2020 by Frankie Leong, who had tended bar at Milroy's of Soho, the oldest independent whisky specialist in London. It began as a haven for whisky drinkers and grew into a bar devoted to fine spirits more broadly, with shelves that reach well past Scotland. By day the room works as a coffee shop, and the coffee is treated with the same care as the drinks poured later. The cocktail list is deliberately short, numbered simply one to ten, and ranges from Spanish brandy to Japanese shochu; an eleventh option is whatever the bar team builds around a guest's taste.
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These are the cocktail bars specifically. The full Macau guide ranks the best bars of every style, and the directory lists all 7 with a map and filters.